Cholestasis in a murine experimental model: lesions include hepatocyte ischemic necrosis
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چکیده
منابع مشابه
Cholestasis in a murine experimental model: lesions include hepatocyte ischemic necrosis.
OBJECTIVE To establish a murine experimental model of bile duct obstruction that would enable controlled observations of the acute and subacute phases of cholestasis. METHODOLOGY Adult male isogenic BALB/c mice underwent a bile duct ligation (22 animals) or a sham operation (10 animals). Fifteen days after surgery, or immediately after the animal's death, macroscopic findings were noted and h...
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ژورنال
عنوان ژورنال: Revista do Hospital das Clínicas
سال: 2003
ISSN: 0041-8781
DOI: 10.1590/s0041-87812003000100006